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Inspired by precedent examples of PLP-dependent enzymes and based on our observations, we propose a mechanism for this transformation catalyzed by CqsA.
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In a precedent example, SYT-SSX was reported to cause aberrant expression of E-cadherin by interacting with either of the tissue-specific transcriptional repressors Snail or Slug [ 41].
"In some countries that do not have full democratic practices, if we get solid assurances, and if there is precedent and we have precedented examples that have occurred, then we feel confident and we do it," he said.
As an example, he referred to the precedent case he tried in late 1997, after the government accused Microsoft of illegally tying a Web browser to Windows.
However, this is not without precedent, for example, central administration of T3 promotes food intake in rats (Kong et al., 2004).
This explanation is not without precedent: for example, both S842A and S842D mutants of GluR4 traffic to synapses in the presence of high magnesium concentrations that prevent synaptic delivery of wildtype GluR4 (Esteban et al, 2003).
Within IMSS, programs like these are not without precedent: for example, IMSS already provides financial support for patients traveling from one city to another to receive medical care, home visits for directly observed therapy for tuberculosis patients, and shuttles for patients with chronic renal failure attending dialysis appointments.
There are some legal precedents; for example, Saks Fifth Avenue Folio is a legal non-tax-collecting direct-mail operation run separately from its high-street sibling.But many of America's biggest traditional retailers consider this strategy too risky.
They conjure Surrealism and Pop Art and are much tamer than their real-life precedents: for example, the actual functioning oil pumps that you drive past in the middle of Los Angeles, fouling the air with dust and fumes on the southern end of La Cienega Boulevard, one of the city's art gallery arteries.
While the film has been rightfully challenged for its flimsy feminist principles ― Elle's knowledge of hair treatments, instead of legal precedents, for example, is what secures her the big win ― how "Legally Blonde" engages with its gay characters deserves more examination.
It is a dangerous precedent and an example of national security extremism.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com