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Because the trial was terminated for futility before reaching the number of HIV infections targeted for pre-planned tests of effectiveness, p-values for those analyses should be interpreted with caution.
Because the trial was terminated well before reaching the number of HIV infections targeted for pre-planned tests of effectiveness (i.e., before any of the type I error was to be spent), p-values for analyses of effectiveness should be interpreted as descriptive statistics.
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"I asked President Hu about it directly, and he said that the test had absolutely nothing to do with my visit and had been a pre-planned test.
After the second stage, the selected treatment group is compared to the control group (using data of both stages) applying the critical value of the pre-planned test.
Pre-planned pairwise tests included each treatment group versus control and CEE + MPA versus CEE and Hi Tib groups.
A pre-planned t-test was used to compare testes weight between PBS and IL-6 receptor antibody treated mice.
Pre-planned t test comparisons were used to determine significance at baseline, in changes within the PLYO and E groups, and at post-test for stature, mass, circumferences, TT performance, and RP.
The use of these methods aided the researchers in understanding human elements of device use in a way that would not be identified via a pre-planned hypothesis testing approach.
Several pre-planned standard psychometric tests for quality of life studies, as outlined in the EORTC Module Development Guidelines, were conducted in our analysis [ 24].
Patients with T-scores ≤-2.5 were given a pre-planned set of laboratory tests that included erythrocyte sedimentation rate (ESR), haemoglobin, leucocytes and serum levels of creatinine, calcium, albumin, alkaline phosphatase, 25-OHD3 and TSH.
Statistical analyses including Student's t-test, Chi-square tests, and GLM ANOVA followed by Tukey's post hoc test and pre-planned contrasts were performed with SAS version 9.3 (Cary, NC, USA).
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