Sentence examples for pre-planned design from inspiring English sources

Two major strengths of this meta-analysis are the inclusion of all phase 3 trials comparing IDeg OD to IGlar OD, and its pre-planned design.

The initial clinical trials developed for registration did not require or measure in any pre-planned design eGFR or GFR as inclusion/exclusion criteria but only serum creatinine concentration.

This pre-planned design for combination phase I trials aims to eliminate chances of falsely halting dose escalation, based on a high a priori chance of developing a DLT of one of the drugs (Hamberg et al, 2010b).

Nothing was pre-planned, designed or thought-through in advance".

In the early stages of the project, Sahuquillo says she painted pre-planned designs but has since embraced the individuality of the model, responding to what each person makes her feel.

This is often the first phase in the waterfall software development model which relies on a pre-planned sequential design procedure [ 22].

We have chosen the intervention effect hypothesised in the sample size calculation as the alternative hypothesis firmly relating the pre-planned trial design to the interpretation of the trial result.

The Chacoans melded pre-planned architectural designs, astronomical alignments, geometry, landscaping, and engineering into ancient urban centers of unique public architecture.

Therefore, the present analysis must be considered exploratory and should be replicated in a larger, pre-planned study designed to formally test the hypothesis that ZOL is effective and cost-effective in a comparable population of RCC patients with bone metastases.

As for the successful CONSORT initiative for randomised trials and for the STARD statement for diagnostic studies, we suggest guidelines to provide relevant information about the study design, pre-planned hypotheses, patient and specimen characteristics, assay methods, and statistical analysis methods.

Combining the estimated effects from the individual centres (studies) using meta-analysis methodology or by stratifying the analysis by centre (or treatment) gives the flavour of a pre-planned meta-analysis, a design used for some time in epidemiology (Blettner et al, 1999; Boffetta et al, 2004; Cardis et al, 2005).