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For the subgroup analyses, the evaluation was primarily through the examination of the LS means for the treatment groups across the different categories or levels of the pre-existing factor and the associated nominal 95% confidence intervals.
Activated recombinant factor VII (Factor VIIa) is a hemostatic agent originally developed for the hemophilia population, but it is emerging as a very effective way of treating uncontrolled hemorrhage in patients without pre-existing factor deficiencies.
It was shown that long-term abstinent alcoholics still present reduced gray matter density within the amygdala [ 14], which may be the result of long-term alcohol abuse or dependence, but may also reflect a pre-existing factor that predisposes to severe alcoholism.
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Long before flooding happens in communities like Mississippi and Louisiana, there are pre-existing factors present that create a dangerous mix for future calamity.
It isn't the referendum vote alone that did this, of course; markets are complex and volatile, and any number of pre-existing factors helped bring us to the crisis we're now suddenly facing.
Individual σ factors can either be regulated by de novo synthesis on the transcriptional or translational level or on the activity of pre-existing factors.
Within each of these themes, three subthemes were identified: 1) pre-existing factors, 2) distribution factors, and 3) redemption factors.
It is probable, however, that these problems are largely explained by the pre-existing factors of boys who become young fathers [ 4].
Earlier reviews of PTSD following childbirth [ 2- 4], [ 16, 17] identified a number of factors associated with PTSD and PTSD symptoms including pregnancy and pre-existing factors, delivery related factors and post-event environmental factors.
Pregnancy and pre-existing factors include tocophobia (fear of labour), depressive symptoms during pregnancy, history of psychiatric and psychological problems, primiparity, unplanned pregnancy, trait anxiety, history of sexual trauma, low self-efficacy and perception of low support.
The model also indicates a role for pre-existing factors and the type of illness or injury in influencing the development of parental trauma, and proposes that each stage is associated with different approaches and targets for intervention.
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