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Besides the ongoing improvements of analytical hardware, standardized methods to analyze and study all proteins have to be developed that allow the generation of testable new hypothesis based on the enormous pre-existing amount of biological information.
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In the absence of clear transcriptional regulation of E2Fs, DPs, and RB transcripts in our different samples (only DPa reached a ratio of 0.5 in early irradiated ATM, data not shown), we hypothesize that translational and/or posttranslational regulation of the pre-existing amounts of transcripts of the RB pathway genes occurred.
According to Carpenter, in chemical screening based on fluorescence-imaging, fluorescence intensity might fluctuate from cell to cell for various reasons, including differences in cell cycle position, stochastic variations in gene expression, pre-existing amounts of proteins and metabolites in each cell and micro-environmental differences (due to cell medium or cell-to-cell-contacts).
Ms. Lewinsky testified that the President's suggestion that they use the pre-existing cover stories amounted to a continuation of their pattern of concealing their intimate relationship.
No pre-existing category of humor.
The park was a pre-existing feature of the city.
They have their own pre-existing pockets of grief.
Forget about pre-existing notions of aria or plot.
Brexit comes on top of pre-existing problems of money and staffing.
"They're not bound by the pre-existing culture of the toy industry," he said.
However, after the revolution not even pre-existing recordings of female singers were broadcast.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com