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To determine the efficacy of pre-emptive administration of the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen vs. a placebo on pain relief during medical abortion and to evaluate whether NSAIDs interfere with the action of misoprostol.
Pre-emptive administration of either clonidine or dexmedetomidine was potent enough to significantly reduce mortality in CLP-induced sepsis.
Nevertheless, pre-emptive administration of either clonidine or dexmedetomidine was potent enough to significantly reduce mortality in CLP-induced sepsis.
Our results demonstrate that the pre-emptive administration of either clonidine or dexmedetomidine have the ability to successfully improve survival in experimental sepsis.
Pre-emptive administration of a central sympatholytic significantly reduced mortality (clonidine: p = 0.015; dexmedetomidine: p = 0.029), although postoperative administration of clonidine failed to significantly prolong survival.
We have shown in this study that pre-emptive administration of clonidine or dexmedetomidine is able to significantly improve survival in sepsis induced by CLP.
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In this randomized controlled trial, we did not observe any beneficial influence of pre-emptive EPO administration on the incidence of AKI and the degree of renal injury following complex valvular heart surgery in patients at risk of AKI.
The aim of this single-site, randomized, case-controlled, and double-blind study was to investigate the effect of pre-emptive EPO administration on the incidence of postoperative acute kidney injury (AKI) in patients with risk factors for AKI undergoing complex valvular heart surgery.
You report that Victoria Toensing, a Justice Department counterterrorism official in the Reagan administration, advocates pre-emptive pardons for administration officials who may have committed crimes to further the Bush administration's policies.
For our study, we chose a "pre-emptive" strategy by administration of lipid emulsions prior to induction of lung injury.
The threat of a veto represents an unusual pre-emptive strike by the administration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com