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In fact, a label placed close to interface generates a strong PRE signal, and thus the PRE profile back-calculated from the native structure already correlates well with the data.
The dependent variable was the differential between minute 1 (pre signal) and minute 2 (post signal) time allocations.
ND, no data; pre, signal peptide (pre-sequence).
How much slack is there in associating a given binding mode with a PRE signal.
This is due to the fact that E32C is close to the edge of the interface in the native complex, already providing a strong PRE signal for residues 67 85, resulting in a high correlation coefficient with the experimental PRE values.
The binding site for this fragment has not been conclusively determined, but the weak PRE signal and modeling of the probe in complex with Lck predicted that it binds in a pocket adjacent to the ATP binding site and the substrate binding site.
Similar(54)
The Palm Pre signaled the resurrection of Palm.
The Pres signal presents two different configurations that permit one to separate between EFL and non-EFL.
We propose a pre-signal threshold method in order to solve this issue.
The pre-signal is one of the noisy optical signals from the S-TOP.
The paper shows how to optimize the design of a pre-signal system for a generic intersection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com