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In a realistic protein protein association the PRE rate, Γ2, is the population weighted average of the Γ2 rates over the native state and the entire ensemble of encounter complexes.
The observed PRE values are the PRE rates averaged over a population (Iwahara et al., 2004; Tang et al., 2006), and hence < Γ 2 (i ) > = (∑ j Γ ji ) / N st where Γji is the PRE rate for residue i of the jth structure in the ensemble.
Considering B as a short-lived encounter complex and A as the native state, and assuming that the system is in the fast exchange regime, the apparent PRE rate, Γ2, is the population weighted average of the Γ2 rates of the two species, that is, Γ2 = p A Γ2,A + p B Γ2,B (Iwahara and Clore, 2006).
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The experimental PRE rates (Γ 2) are displayed as filled-in magenta circles.
The correlation coefficient between the experimental PRE rates and the ones based on the encounter complexes is 0.705.
The experimental PRE rates (Γ 2) are displayed as filled-in magenta circles (Tang et al., 2006 ).
In contrast, the correlation coefficients between the experimental PRE rates and the ones back-calculated from the native structure (black line in Figure 2A) is only 0.47.
They have become big businesses, moving into ever more exotic financial instruments, offering to pre-rate securities planned by an issuer, and selling advisory services.
The explanation lies in the relatively faster rate of the pre-rate-determining step (CO2 insertion) which ensures that, from a mixture of monomers, catalyst 1 selects for ROCOP.
N: sample size, Pre: prevalence rate of human infection with S. haematobium.
Three of those terms were made-up ("pre-rated stocks," "fixed-rate deduction" and "annualized credit").
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

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