Plutonium cannot be used as the fissile material in a gun-assembly device, because the speed of assembly in this device is too slow to preclude the high probability that a chain reaction will "pre-initiate" by spontaneous neutron emission, thereby generating an explosive yield of only a few tens of tons.
These results suggest that while nicotine has only limited capacity to initiate tumor formation, it can facilitate the progression and metastasis of tumors pre-initiated by tobacco carcinogens.
Tumor promotion considers the pathological incidence in which non-genotoxic carcinogens, such as chronic PB treatment, determine tumor development in organs pre-initiated by genotoxic carcinogens such as diethylnitrosamine [28].
The mitophagy pathway was pre-initiated with a 20%% fraction of ROS-activated Bnip3, which we defined based on a relative increase in Bnip3 receptor binding to LC3B upon enforced LIR activation [ 14].
Some breast cancers may be pre-initiated in utero following an exposure to elevated maternal oestrogen levels that stimulate the growth of foetal mammary gland and might cause long-lasting alterations in the expression of oestrogen-regulated genes (Trichopoulos, 1990; Hilakivi-Clarke et al, 2002).
PREs initiate and maintain PcG-silencing, and PcG protein-dependent PRE−PRE interactions increase their activity (Delest et al. 2012; Kassis and Brown 2013).
Relatively minor phenotypic distinctions may allow pre-neoplastic initiated cells to evade the selective pressure exerted by FAC at this concentration.
Pre-enrichment was initiated with BPW pre-warmed to 37°C and pre-enrichment was performed for 6 7 h at 37 ± 1.0°C.
Although pledging is explained away as a period of time during which pre-initiates ("pledges") devote themselves to learning the information necessary to become full members, in reality, it is often the vehicle for demeaning activities that cause psychological harm and physical danger.
Although cohesin is absent from the transcription units of PcG-silenced genes, it binds many polycomb response elements (PREs) that initiate and mediate silencing (Misulovin et al. 2008).
Hazard ratios for factors associated with having a longer time to ART initiation in a cohort of 138 children who initiated pre-ART care during the period 2003 2008.
