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In this work, pre-formulation studies concerning the design of novel mucoadhesive films have been carried out.
We report results of a recently-completed pre-formulation phase study of SPIRIT, a candidate NASA Origins Probe mission.
A common problem in pre-formulation is the optimization of the mixture composition which is aimed to obtain a product with the required characteristics.
This thorough pre-formulation study represents an important advance towards the development of an efficient pre-anesthetic for use in dentistry.
Non-human in vitro and in vivo taste-evaluation tools are very useful for pre-formulation, quality control and screening of formulations.
A common problem in pre-formulation of the cosmetic product is the optimisation of the mixture composition aimed to obtain a product with the required characteristic.
These data can either be determined during pre-formulation studies on e.g. polymeric flat films or from in-vitro release measurements of the actual coaxial fibers.
Project pre-formulation activities are marked by extensive technology development necessitating early, but realistic, thermal and cooling load requirements for ADR and ACTDP-cryocooler design points.
It has been found that the permeability data obtained in the pre-formulation studies are useful in semi-quantitative terms, but deviate from the permeability data found from the in-vitro release of coaxial fibers.
The objective of this pre-formulation study was to systematically investigate the effects of two surfactants (Brij 58® and Tween 80®) and change in solution pH on in vitro permeation of naltrexone HCl (NTX-HCl) across tissue engineered human buccal mucosa.
Well, the irony is that such pre-formulation can help you clarify things.
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