Sentence examples for prb by from inspiring English sources
Phosphorylation of retinoblastoma protein (pRb) by Cdk2 is the penultimate step in the transition from G1 to S phase.
Then, the maximum achievable throughput is computed by multiplying throughput per PRB by the number of assigned PRBs obtained in (4).
Each user estimates the probability that a given MCS level is estimated on each PRB by accumulating the number of PRBs supporting the corresponding MCS level among all the PRBs [18].
It is reported that one mechanism of the inactivation of pRb by E7 is the targeted destabilization of pRb [11], [12], [36], [37], [38].
Therefore, it is reasonable to speculate that Pep-7 may rescue the tumor-suppressing function of pRb by releasing it from the HPV E7/pRB complex and preventing its degradation induced by HPV E7.
Like the E2F-binding sites mutation, knocking down pRb by siRNA abolished the effect of Pep-7 on these E2F response promoters, whereas the selected peptide-mediated inhibition of the above promoter activities did not changed with the p107 and p130 knocked-down (Figure 6B).
Moreover, there is evidence that E2F1 is activated by the E7 protein of HPV-16 in a pRB-independent manner [ 54], apart from its pRB-dependent activation, which in the case of HPV infected cells is also promoted by pRB inactivation by viral oncoprotein E7.
The position of the RN corresponds to an MCS of 16 and a TBS of 1608 bits per TTI with the allocation of 5 PRBs by DeNB.
Results were then used to compare removal against activated carbon and aggregate-based PRBs by estimating material costs for the remediation of an example heavy metal contaminated Superfund site located in the Midwestern United States, Joplin, Missouri.
The E2F transcription factors can be blocked by the tumour suppressor protein pRb encoded by RB1 that was overexpressed.
We therefore conclude that the decrease in cyclin A is not directly mediated by p38, but rather a consequence of inhibition of pRB phosphorylation by SB203580.
