JRH and PSC developed the mechanical ventilation and dialysis practice pattern characterization tools.
We hope that in due course, the best-practice characterization procedures can be adopted.
This article targets medicinal chemists and drug design teams and provides general definitions of fundamental PK parameters together with the best-practiced characterization, optimization, and prediction strategies employed in the authors' laboratory.
Our approach was guided by the notion of "knowledge-as-practice" as advanced by Knorr Cetina (1999) who studied scientists and characterized their knowledge as practice, a characterization which shifts focus away from ideas inside scientists' minds to practices that are cultural and deeply contextualized within fields of science.
This information and the reported methodology should be standard practice for characterization of QD SAv conjugates prior to further conjugation.
In standard clinical practice, this characterization is usually achieved by conventional cytogenetic approaches only, thus submicroscopic imbalances at the breakpoints will remain undetected because of the low resolution of such approaches.
As currently practiced, risk characterizations do not convey the degree of uncertainty in a risk estimate to risk managers, Congress, the press, and the public.
Already, great strides have been made to translate these early discoveries into clinical practice, and the characterization of novel mutations in chromatin modifier genes is rapidly accelerating.
Imaging is used widely in oncologic practice for lesion characterization, confirmation of diagnosis, staging, treatment planning, targeting therapy, assessing treatment response, and surveillance.
The current practice of crash characterization in highway engineering reduces multiple dimensions of crash contributing factors and their relative sequential connections, crash sequences, into broad definitions, resulting in crash categories such as head-on, sideswipe, rear-end, angle, and fixed-object.
