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Such information has implications for clinical practice and the classification of mental disorders.
These include the complexity of the system (30,000 DBCs in practice) and the classification of diagnoses which lacks uniformity.
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In practice, the classification of mutations as drivers and passengers is based on their location at positions considered to be important because of their evolutionary conservation, and on observations in other experimental datasets (for a review of the methods used to classify driver mutations and the role of tumor progression models, see [ 74]).
As participating GPs practiced the classification of MUS during the study period, they were able to discuss hands-on experiences in the focus group interviews rather than just theorise about the new diagnostic category.
The questionnaire addressed physicians' age, gender, level of education, number of years since accreditation, part-time or full-time work, major language used, practice organization (group or solo practice; level of urbanization of practice location according to the classification of the Swiss Federal Statistical Office) and technical equipment (ECG, ultrasound, X-ray and laboratory).
They relate to the sensitivity and specificity of the tests that are used for the diagnosis for which practice patterns are being evaluated and for the classification of the outcomes of interest.
Although more studies are required to establish the feasibility of this technique in clinical practice and for classification of motility disorders, it seems a promising tool for assessing the severity of disease [37].
Patients are eligible for participation if they present in general practice with CTTH according to the classification of the International Headache Society (IHS).
Table 2 presents a matrix of the units' profiles for the two actual scope of practice factors and the resulting classification of the units for this dimension.
Because of the need for timely information regarding their quality, a common business practice is to establish procedures for the classification of used products (returns), which is not always error-free.
The classification of this practice as mandatory is aligned with the practices selected for the Planning phase, some of which related to risk analysis.
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