This demonstrates the competence of the binding and translocation domains of PE to mediate delivery of the DTA and RTA catalytic domains into cells cytoplasm and, importantly, that NS3 cleavage mediated enhancement in the enzymatic activity of the two zymoxins (as was detected by in-vitro assays) is practically translated to enhancement in cytotoxic activity.
Given that 40% CR is likely too severe to be practically translated in human studies and might be detrimental to the liver, and that 20% CR had minimal effects on gene expression, we decided to focus on the effects of 30% CR on mammary fat pad gene expression and tumor burden.
Others considered it unlikely a rights discourse could practically translate into measureable targets, or 'value add'.
A consideration of these practicalities at the preclinical phase may accelerate the selection of new strategies that can be practically and rapidly translated to the clinic.
"Very simply put, value is for every dollar spent, how much you get out of it," says Edwards. "But that can be translated emotionally, practically or in a number of ways".
This has been translated into practically every other industry.
You will have access to a treasure trove of Russian and Soviet anecdotes and jokes which, like tipsy dinnertime conversations, are at once ludicrous and moving and often practically impossible to translate into English.
(The business is a firm of solicitors, which translates, practically speaking, to personal bankers or brokers.) Coolly explaining to his perturbed son the practice of borrowing from one client's account to pay dividends due to another, he sighs, "Oh, why is it so hard for a man to see clearly beyond the letter of the law!" It is not so hard, if such double vision serves a man's personal interest.
Practically, that should translate into more NOAA ships, equipment, and technology going to Cuba, which has a dearth of research resources, Whittle says.
Our experimental results and DFT calculations show that at low surface coverage, due to the very low corrugation of the adsorption potential, and in the absence of H2 H2 lateral interactions, the adsorbed molecules are practically free to translate in the 2D plane parallel to the surface.
Depending upon the efficiency of time-management in the laboratory, 2.62 FTHOE staff translates practically to the equivalent of 5 6 staff being employed to manage the smear microscopy workload.
