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To improve the clinical practicality of the nomogram, we assigned a cutoff value, derived from the Youden index, to the nomogram to allow for the prediction of dichotomous outcomes for metastasis.
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Students marked the distance on the left of the nomogram and the amplitude on the right of the nomogram, then using a straightedge would connect those two marks.
Figure 2B illustrates the calibration plot of the nomogram.
The c-index of the nomogram was 0.719.
Discrimination of the nomogram was quantified with the concordance probability.
Despite good performance of the nomogram in a separate data set, concerns related to the generalisability of the nomogram remain.
To overcome this and increase statistical simplicity of the nomogram, we limited the numbers of predictors used to build the nomogram according to the guidelines of Harrell [ 14].
It smacked of practicality, of the outdoors.
The practicality of the method has been demonstrated.
Practicality of the sensor was demonstrated in human urine samples.
These characteristics greatly degrade the practicality of the fingerprinting protocol.
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