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However, an associated increase in bleeding and the practical difficulties of managing warfarin limited its introduction to routine practice.
The practical difficulties of conducting any survey may also introduce other sources of error.
They discovered important new facts and solved the great practical difficulties of preparation.
But the practical difficulties of forcing change on private contractors appear to have been underestimated.
Others pointed out the practical difficulties of enforcing the new legislation.
The practical difficulties of using a medium that has to be kept warm are considerable, though.
We will also discuss the practical difficulties of writing and do an introductory exercise in class.
The practical difficulties of trying to draw judicial lines on what is "interstate commerce" are also great.
This contributed to the practical difficulties of power-based sample size planning, common to novel experimental approaches46.
Finally a real-life case is used to illustrate some practical difficulties of the method.
The reforms illustrate both the political risks and practical difficulties of cutting the welfare bill which, together with pensions, forms Whitehall's biggest budget.
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