Exact(6)
Our improved method based on a discrete genetic algorithm is still probabilistic and obtains good approximations for large numbers of peaks in a practical amount of time.
The presented solution, which has been demonstrated to approximate the optimal solution in a practical amount of time, is among the few that address the computational challenge.
In the meantime, there remains a need for techniques that apply external forces to explore conformational changes in a practical amount of time.
However, in order to complete the experiment in a practical amount of time, we purposely exaggerated the absolute parasitism risk by forcing the crickets to associate with a high amplitude song (to attract a sufficient number of flies) for a longer period (to allow sufficient time for parasitism to occur).
FastTree software can handle large alignments in a practical amount of time and memory.
In the sensitivity test, we compare against MegaBLAST because it is generally considered one of the most sensitive heuristic aligners for finding a large number of alignments in a practical amount of time.
Similar(2)
Two advanced features of Murasaki are (1) adaptive hash function generation, which enables efficient use of arbitrary mismatch patterns (spaced seeds) and therefore the comparison of multiple mammalian genomes in a practical amount of computation time, and (2) parallelizable execution that decreases the required wall-clock and CPU times.
This simulation study demonstrates empirically that the GKONP algorithm has achieved good accuracy in a practical amount of running time.
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