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The remaining list was further shortened to the demands of a short and practicable scale measuring sleep and cognitive, emotional and behavioural symptoms of PI.
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Approaches to ecological small-area analysis propose using the smallest practicable spatial scale for any study on inequalities in health [ 8, 9].
We improved and combined two genetic methods of clonal analysis that together make practicable large-scale production of labelled clones.
For example, reproduction of results in the same or different laboratories as a prerequisite for publication is not practicable for large-scale DNA sequencing of random molecules because of constraints on time, costs, and sample materials.
In many cases this is not practicable on a large scale and consequently there is a reliance on unsorted tissues.
Therapeutic use of CFH delivered by 2-weekly intravenous injection of fresh frozen plasma (half-life 6 days) (46) is not practicable on the necessary scale, but local delivery of an inducible recombinant CFH to the choroid or retinal pigment epithelium by a viral vector may be more achievable (47, 48).
None of the scales has thus proved practicable enough to be used in clinical situations like nursing practice on a daily basis.
In the early 1950s Spedding and his associates at the Ames (Iowa) Laboratory of the U.S. Atomic Energy Commission developed a practicable and efficient method for large-scale preparation of thorium metal.
Thus, an industrial-scale reactor should be practicable.
Further simplification and standardisation of regimens would make scaling up treatment more practicable, but potentially increases the risk of XDR-TB development.
By pre-computing the required data at the micro- and meso-scales and storing them in a look-up table, these small-scale effects can be captured in a macro-scale model that executes with practicable execution times.
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