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In each arm, assuming a practicability rate of 50%, 50 patients were to be evaluated to detect a practicability rate of >30% with 90% power at the 5% significance level.
The aim of the trial was to detect a practicability rate of >30% for each arm, respectively.
The primary analyses were the two-sided 95% confidence intervals of the practicability rate for each arm.
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The rate of practicability (as defined above) was 52.4% (22out of 42) in arm A and 42.2% (19 out of 45) in arm B, respectively (Table 3).
The rate of practicability was 42.2% with a 95% CI of 28 58%, including the 30% limit hypothesised; thus missing the aim of the study.
The primary endpoint was rate of practicability as defined: application of ⩾2 cycles of therapy (1) with a maximal delay of 1 week (2) and survival of ⩾8 months (3).
In this paper, the reliability and practicability of using high-rate carrier phase global positioning system (GPS) receivers are investigated to characterize dynamic oscillations of bridges.
Additionally, a qualitative evaluation of the used check systems was performed, employing a questionnaire asking five pain physicians to compare and rate the performance and practicability of the three CDSSs.
Lessons from the feasibility trial will be used to refine the intervention and gather the information needed for a definitive trial such as practicability of the intervention, recruitment and retention rates and effect sizes, and variance required for a sample size calculation.
This amphiphilic prodrug has a unique molecular structure with prominent features, including strong practicability for methacrylate prodrug monomer, high drug loading rate (up to 23 wt%), adjustable proportion of hydrophobic and hydrophobic portions, superior stability in aqueous solution, and easy access to cells.
This is likely to increase both the practicability of the tool and, consequently, student response rates.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com