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Considering the lack of any response induced by 50 ppm concentration of lead, it may be concluded that 100 ppm of lead was the minimal effective dose.
And eggs could easily become even more contaminated: Those they tested came from chickens living on soil that maxed out at about 600 ppm of lead, but levels greater than 1000 ppm are common in some cities.
The logo on a Florida Gators lunch bag manufactured in China, for example, contained almost 2,000 ppm of lead.
One of those yards clocked in at 2,760 parts per million (ppm); the EPA's upper limit for soil that children play in is 400 ppm of lead.
"The can would say 'no added lead,' but then there may be 20,000 ppm of lead," said Scott Clark, professor emeritus of environmental health at the University of Cincinnati and a co-author on the IPEN report.
The analysis would find an unexpected level of 226 parts per million (ppm) of lead in the crewman's bones, which was 10 times higher than the control samples, taken from Inuit skeletons from the same geographic area, of 26 36 ppm.
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To model gestational lead exposure (GLE), one group of dams received tap water or drinking solutions containing low (27 ppm), moderate (55 ppm), or high (109 ppm) concentrations of lead beginning 2 weeks before mating and continuing until postnatal day 10.
Briefly, female mice fed Purina lab chow 5001 (Purina Mills, St . Louis MO) were given water (control) or water containing a low (27 ppm), moderate (55 ppm), or high (109 ppm) concentration of lead 2 weeks before mating, during pregnancy, and through PND10 to produce a human-equivalent GLE.
We exposed female C57BL/6 mice to water containing 0, 27 (low), 55 (moderate), or 109 ppm (high) of lead from 2 weeks prior to mating, throughout gestation, and until postnatal day 10 (PN10).
Environmental Protection Agency EPAapprovedved the maximum threshold limit of 0.015 ppm for lead in drinking water.
The United States has set limits of 600 ppm for lead in new paint for residential use and less than 5,000 ppm for paint in existing housing; paint containing at least 5,000 ppm lead is considered to be "lead-based".
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