Sentence examples for ppi development from inspiring English sources

Simultaneously, the ionospherically reflected pump wave signal exhibits a recovery of ponderomotive self-action and the damped quasi-periodical oscillations (spikes) of the reflected pump wave, also related to the PPI development.

Targeting protein protein interactions (PPIs) for development of therapeutic molecules poses the problem of tethering a small molecule to a large, featureless protein surface.

Twenty-six applications (26/90=28.9%) specified a role of PPI within the development of the outline application.

Incorporation of PPI within the development of the outline application or specification of plans for future involvement was low.

54% (49/90) provided some information about PPI. 26 (28.9%) indicated PPI within the development of the outline application itself; 32 (35.6%) planned involvement in the full application and 43 (48%) once the trial was funded.

Further PPI into its development included it being discussed at a recent quality improvement initiative which included patients who had been users of our service and stakeholders ranging from clerical, administration staff through to managers, medics, nurses, midwives and allied healthcare professionals.

Targeting protein protein interactions (PPIs) for therapeutic development was once considered undruggable due to the large and flat interactive surfaces that lack cavities.

Novel PPIs are in development, including a competitive inhibitor that reversibly binds near the K+ binding site of the H+/K+-ATPase.28 The clinical effectiveness of these so-called acid pump inhibitors compared with existing PPIs has yet to be determined.

Protein protein interactions (PPIs) are involved at all levels of cellular organization, thus making the development of PPI inhibitors extremely valuable.

Therefore, future research directed at PPI target discovery, PPI interface characterization, and PPI-focused chemical libraries are expected to accelerate the development of the next generation of PPI-based anticancer agents.

To increase knowledge of PPI within the early development of RCTs by systematically describing the reported level, nature and acceptability of proposed PPI to the funders.