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Given misoprostol's potential to reduce PPH, it is increasingly being made available in low-resource settings where the majority of PPH occurs.
Unlike oxytocin, the preferred uterotonic in the management of PPH, it can be administered orally/sublingually instead of parenteral.
This result highlights a statistical association between intended place of birth and PPH; it does not prove a causal relationship, nor does it explain why the association exists.
It is important to be cognizant of the fact that despite the growing body of literature on the known risk factors for primary PPH, it maybe inevitable in some cases.
When attempting to use coagulation status to predict PPH, it is important to remember that, unlike many clinical settings, substantial blood loss may be considered 'normal' in obstetric patients.
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AMTSL is an important tool in preventing PPH, however, it must be clarified how it should be used in countries with scarce resources.
Selective arterial embolisation (SAE) of the uterine arteries was recently proposed as an alternative to surgery, and success rates for controlling severe PPH with it are reported to range from 85% to 95% [13], [16].
Its main objective was to evaluate a multifaceted educational intervention for reducing the rate of severe PPH, and it found no significant difference in this rate between the two groups of hospitals (details available elsewhere 25).
Biochemical studies showed that it has decapping activity (toward both GpppRNA and mGpppRNA) as well as a distributive 5′ 3′ exoribonuclease activity, although it lacks PPH activity.
Identifying PPH cases presents its own difficulties.
"Yet if you are calling for help, nobody is coming, so it is difficult for that PPH to be managed as proper as it can be" (nurse midwife).
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CEO of Professional Science Editing for Scientists @ prosciediting.com