Drab, featureless and phallocratic is how Johnson described the rash of 27 tall buildings that Ken Livingstone had waved through, a pox that was fast threatening to turn London into "Dubai-on-Thames".
This is done by increasing acetate production through the pox or pdh steps (see below), increasing the flux through the glyoxylate shunt and thus bypassing the main TCA cycle.
So "Pox Americana" sifts carefully through journals and records of the late 18th century to reconstruct the path of the disease.
She had nursed them through chicken pox, taken them to Coney Island and held them in her arms until they fell asleep.
Following PQ exposure, an increased production of acetate through the pox or pdh-ace step was evident by the large increase in the residual acetate level in the cell culture medium.
Having shown that POX is activated by oxLDL through PPARγ, and POX initiates autophagy through the induction of beclin-1, the mechanism for the POX-mediated effect becomes critically important.
(24) The HETEs arise from reduction of the corresponding hydroperoxyeicosatetraenoic acids (HPETEs) primarily through the peroxidase (POX) activity of COXs.
POX is upregulated by oxLDL through PPARγ and plays a key role in the regulation of protective autophagy in cancer cells.
This last fact links POX to autophagy, a process regulated mainly through the mTOR pathway.
