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Interestingly, in contrast with the lack of effect of siRNA-mediated suppression of HIF-2 α, overexpressed HIF-2 α powerfully activated the PHD3 HRE.
Adriamycin powerfully activated the DNA damage checkpoint so that essentially all Jurkat cells accumulated in G2,M with 4N DNA content within 24 hours of treatment (Fig. 4B, inset).
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We know that these expectations powerfully activate the brain's reward pathway, which runs on dopamine, a chemical released in the brain in response to anticipated pleasures: sex, food and money, to name a few.
Previous findings have shown that the superantigen staphylococcal enterotoxin A (SEA) not only powerfully activates T cells, but also induces broad expression of genes related to cytokine production and TCR signal transduction [ 27– 29], implying that SEA may affect the expression of early kinases in the TCR signaling pathway.
The IKKs respond to many physiological stimuli, but are activated most powerfully by inflammatory stimuli, such as TLR (Toll-like receptor) agonists and the pro-inflammatory cytokines IL-1 (interleukin-1) and TNF (tumour necrosis factor).
However, Irving et al. reported that acidification of guard cell cytosol by kinetin, IAA or FC preceded stomatal opening (Irving et al. 1992), H+-ATPase could be activated by FC powerfully (Marrè 1979; Beffagna et al. 1977), and a decrease of endogenous H2O2 levels were associated with auxins- and cytokinins-induced stomatal opening (Song et al. 2006).
These autocrines powerfully trigger cell proliferation and tumor angiogenesis [ 34– 34].
When myocytes in remote regions are subsequently activated and start to contract, they contract even more powerfully due to the early systolic pre-stretching (known as the local Frank Starling mechanism) [ 4].
He activated the alarm.
Cruise control is activated.
Twitter was then activated.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com