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There are powerful oxidative stress response systems.
Recruited polymorphonuclear neutrophils (PMNs) rapidly generate reactive oxygen species, mediated by a powerful oxidative burst, thus immensely increasing oxygen consumption.
Among different AOPs, Fenton process is one of the most powerful oxidative treatments operated at room temperature and pressure.
In Nature, microorganisms often encounter this same problem during biomass turnover wherein powerful oxidative enzymes produce heterogeneous slates of aromatics compounds.
Electronic, lipophilic and steric descriptors included in QSAR-2D and -3D are analyzed for a set of ortho- and para-naphthoquinones that have proved to be powerful oxidative agents with potent trypanocidal activities specially against Leptomonas seymouri and Trypanosoma cruzi.
We induced acute anemia by injecting Sox6fl/fl and Sox6fl/+ErGFPCre control mice and Sox6fl/flErGFPCre mutant mice with phenylhydrazine (PHZ), a powerful oxidative agent [37].
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The direct toxicity of NO is modest, but is greatly enhanced by reactions with superoxide (O2-) to form the powerful oxidant peroxynitrite (ONOO-), which can promote oxidative damage to blood vessels and skin.
It is suggested that oxidative injury, especially lipid peroxidation, via a powerful oxidant (e.g., hydroxyl radicals), may play an important role in cerebellar degeneration during MeHg intoxication.
Oxidative stress could be a major player in mitochondrial damage, and previously Herman et al. reported an increase in peroxynitrite, known to be a powerful oxidant, in imatinib-treated rat ventricles.
The most powerful canonical oxidative stress-related protein was CAT, which increased the median survival of Arctic Aβ1 42 flies by 56% (P < 0.0001, Fig. 4a and c).
Moreover, it has been suggested that cancer chemo-prevention and treatment should focus on the development of new powerful anti-oxidants to minimise oxidative stress, L-Lactate production and tumour stromal co-evolution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com