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Lastly, with the increasing availability of radiotracers and novel compounds for molecular and physiological assessment, including labelling of target cells and compounds that target particular cell lines or processes, the combination of these powerful modalities may result in significant advances for research (and potentially clinical) purposes.
Tissue engineering techniques can be powerful modalities to improve the effectiveness of nerve conduit bridging.
Therapeutic monoclonal antibodies (TmAbs) that block tumor necrosis factor are powerful modalities in the treatment of various inflammatory diseases, but both chimeric and human TmAbs can induce anti-TmAb antibodies.
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This sustained and controllable growth factor delivery system, with independently controllable physical and cell adhesive properties, may provide a powerful modality for a variety of therapeutic applications.
Multispectral optoacoustic tomography (MSOT) is a powerful modality that allows high-resolution imaging of photo-absorbers deep within tissue, beyond the classical depth and resolution limitations of conventional optical imaging.
Since LVs can transduce a wide array of cells, support long-term gene expression, and be modified to enhance cell targeting, LVs are a powerful modality to deliver life-long therapeutic proteins.
This further highlights its potential to be a powerful modality for assessing tissue flaps and preventing their failure.
Multifunctional nanoparticles (NPs) that enable diagnostic imaging and therapeutic drug delivery are rapidly emerging as a powerful modality in cancer therapy.
Given the number of new agents, delivery variables, and all possible combinations, testing in classical clinical trials for the most powerful modality will be impractical.
PAT, as an emerging powerful modality, has the capability to image the structural and functional information of biological tissues with high resolution and satisfactory imaging depth [ 1– 4].
Although US is a powerful modality for differentiating malignancy from benign focal thyroid nodules [ 13, 15, 34], some studies have speculated that it might be difficult to detect malignant nodules in patients with HT on US because the heterogeneous hypoechogenicity and micronodulation seen in HT are somewhat similar to features seen in malignant thyroid nodules [ 2, 12].
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