Sentence examples for powerful differentiation from inspiring English sources

Given that MSCs attain powerful differentiation capabilities and also present immunosuppressive properties, which enable them to survive host immune rejection, MSCs are of great interest.

Umbilical cord mesenchymal stem cells (UCMSCs) retain their intrinsic stem cell potential while at the same time displaying high proliferation rates, powerful differentiation capacity, and low immunogenicity.

BDNF is a powerful differentiation factor distributed widely in the central nervous system (CNS), and its concentration is particularly high in the hippocampus [24].

MDIT is a more powerful differentiation cocktail, and hence little additional triacylglycerol accumulation was seen with SRA overexpression in MDIT-treated ST2 cells (Figures 2B and S1A).

However, SRA has very little effect on adipogenesis in response to the more powerful differentiation cocktail MDIT, presumably because troglitazone allows for strong PPARγ signaling even when SRA levels are low.

In addition to being a powerful differentiation-inducing agent, ATRA can inhibit growth in some colon cancer cell lines [ 48].

Furthermore, MSC conditioned medium is a powerful astrocytic differentiation-inducing agent in cultured human U251 glioma cell line.

S1P acts as a powerful pro-differentiating agent by enhancing the expression of myogenic differentiation markers such as myogenin, myosin heavy chain, and caveolin-3 [32], [33], [33].

Our results also demonstrate that substrate immobilization of IGFBP4 is a powerful tool for differentiation of ESCs into cardiomyocytes.

TNFα would appear as an interesting candidate since it is a powerful inhibitor of differentiation of human preadipocytes [12] and, in addition, activates Wnt signaling [21].

Importantly, IGF-I in the brain modulates lifespan in mammals (Holzenberger et al., 2003; Kappeler et al., 2008) and is also a powerful cell proliferation, differentiation, and survival factor (Aberg et al., 2000; Kalluri et al., 2007).