Sentence examples for power to detect polymorphisms of from inspiring English sources

Figure 2 indicates that IgC2N has at least 80% power to detect polymorphisms of frequency 5% in datasets of sample size 200 which are at least 100 kb long or have at least 10 covering markers.

However, the presence of multiple QTL acting in the same direction can decrease the power to detect a polymorphism of small effect compared with the case in which it segregates alone (Yang et al. 2013).

Among BRCA1 mutation carriers and at a threshold of p < 0.0001, CIMBA currently has a power of over 80% to detect polymorphisms with minor allele frequencies greater than 10% that confer risk ratios in excess of 1.2 (Table 1).

This sample size gave us enough power to detect all polymorphisms that occur at a frequency >1% in this population.

The markers were used to detect polymorphisms between NIP and '93-11 '93-11

The average power to detect association of ITGAM polymorphisms was 84% in DLE and 91% in SLE.

This might include the absence from a large series of ethnically matched controls or MODY patients (testing of 210 normal chromosomes is necessary to achieve at least 80% power to detect a polymorphism present in 1% of the population [ 35]).

A contributing factor to the observed difference between the sexes may be that there is less statistical power to detect expression polymorphism in the female experiment.

The study has over 80% power to detect main effects of common polymorphisms (minor allele frequency of 5% or greater) with relative risks of 1.2 or greater, and to investigate interactions between genetic variants and known environmental or lifestyle exposures [ 18].

Acknowledging that the majority of selected polymorphisms have a minor allele frequency of at least 30% and using an α of 0.005 (with a Bonferroni correction for 14 polymorphisms), 1008 children will provide 80% power to detect an OR of 1.5 between each polymorphism and admission.

Hence, polymorphism data may offer higher power to detect the effect of selfing on the efficacy of selection.