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The lower number of non-cured patients limited the statistical power to detect determinants of unsuccessful treatment.
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Backwards stepwise logistic regression was employed to detect determinants of a capillary MFI < 2.6.
It is therefore possible that a cohort of 500 people will yield sufficient power to detect meaningful determinants of successful ageing and change in function and mood.
Lastly, because of the extensive efforts to encourage participation that were implemented throughout the fieldwork, our attrition rates were relatively low and thus our statistical power to detect significant determinants of participation was reduced.
In addition, a multiple logistic regression analysis was conducted to detect determinants for the use of GPI.
The study is non-invasive, imposes no risk on patients, seems to have enough power to detect meaningful determinants and our protocol has been approved by the medical ethical committees.
At an α of 0.05, a sample of 800 children had 80% power to detect an RD of admission of ≥7.5% for all key determinants.
Our study was powered to show an association of clinical relevance between measures of low fertility and T2D, as we had 80% power to detect a HR of 1.4 for determinant variables with a 10% prevalence, when including both prevalent and incidence cases.
The WECARE Study was based on the premise that by restricting consideration to women with a first primary breast cancer and then studying the determinants of developing a second primary breast cancer, the power to detect main effects of relatively rare genetic mutations and their interactions with environmental factors is considerably enhanced.
The small size of some groups also limits the power to detect some of these interactions.
This creates phenotypic variation that may result in less power to detect the genetic determinants for physiological differences or inconsistency in detected QTLs across time.
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