Sentence examples for power of linkage from inspiring English sources

If imprinting plays a role in the heritable etiology of ASD, the power of linkage analyses to identify susceptibility loci may be improved by accounting for allelic parent-of-origin.

Further genetic dissection of this locus is limited by the power of linkage analysis and the mosaic structure of the murine genome, leading to a high degree of linkage disequilibrium in the region of interest [45].

For this reason, incorporating DNA methylation data with association and linkage analyses may provide new insights for correlating genetic markers and disease, and thus increase the power of linkage and association studies.

These results may explain the better power of linkage analysis using this "subgroup" strategy.

This process is an important methodological development to increase the power of linkage studies when all individual data elements are not available for all individuals.

The strength of the NAM method is that it combines the power of linkage mapping with the resolution of association mapping.

The statistical power of the linkage population was 65% for a causal mutation which explained 2% of the phenotypic variation when using the linkage population only under assumption that the minor allele frequency (MAF) of the mutation is at a middle level (30%) [41].

And it is the partners, not the presents, upon whom reciprocal exchange confers its quasi-mystical power of social linkage.

We demonstrated that using clinical information, unaffected siblings, and family history can increase the analytical power of a linkage study.

Additionally, the SNP haplotypes were subsequently used to validate the power of nonparametric linkage analysis (NPL) of the SNP data to identify shared regions in small kindreds.

But the LOD scores (Fig. 1) are much higher than those from individual family mapping [21], which empirically demonstrated the higher mapping power of joint linkage analysis.