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Conservation from greater evolutionary distances may improve discriminative power in identify functional nucleotides, but with the potential trade off of detecting a smaller set of conserved alternative splicing events [ 29].
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On the other hand, the non-linear methods such as Markov switching identify adequately the periods of big recessions, but they lose power in identifying the recessions after 1990.
It was found that a large proportion of allosteric modulators (80%) can be successfully retrieved by this "allosteric-like" filter, which shows good discriminatory power in identifying allosteric modulators.
Gross violations will result in a reduction of power in identifying true targets.
In addition, some methods have been shown to predict health outcomes; for example, monofilament examination has shown significant predictive power in identifying individuals with neuropathy due to diabetes and leprosy who are at greatest risk of experiencing foot ulcerations.[6], [17] However, these techniques must be validated in resource-constrained settings to ensure feasibility and accuracy.
Benjamini Hochberg FDR is also included in the software to have more power in identifying enriched terms (22).
Larger cohorts will be pivotal for increasing power in identifying and validating causal variants of high and modest effect size.
Proteome and secretome analyses show exceptional power in identifying proteins and in tracing the complex circuitry of signals involved in tumor progression [ 23].
FM had the greatest power in identifying pathways that were considered to be large compared with pathways that were smaller in size.
As previously reported, LA is known to have a higher power in identifying mixed genotypes, but the clinical implication of this higher power is not well established [ 8, 9, 16].
This study shows that in NSAID users, percent change in H. pylori IgG-antibody titers has better diagnostic power in identifying H. pylori negative patients at both 3 and 12 months than absolute change in H. pylori IgG-antibody titers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com