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Investigations were performed using carrageenan induced rat air pouch model.
Alginate microbeads, ionic (unmodified) and dual crosslinked, were implanted into a rat omentum pouch model.
Stimuli-responsive Au NCs were applied in a hamster check pouch model carrying early-stage squamous carcinoma tissue.
Both compounds exhibit anti-inflammatory effect in the dorsal air pouch model of inflammation as shows by inhibition of PGE2 secretion.
In the animal study, the scaffolds were combined with rhBMP-2 and ZA, rhBMP-2 or implanted alone in an ectopic muscle pouch model.
The optimized formulation was fabricated into the transdermal patch and in-vivo pharmacokinetic and pharmacodynamic study (subcutaneous air pouch model) was carried out.
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This was investigated in vivo using a mouse air-pouch model of inflammation.
The M1/M2 phenotypic polarization profile of macrophages was investigated in vivo using a rodent air-pouch model.
The in vivo effect on leukocyte migration of these compounds was investigated by using the mouse air-pouch model of local inflammation.
In order to investigate if the necrotic cell death caused by activated NLRP3 induced a neutrophilic inflammatory response, we performed neutrophil infiltration assays using an air-pouch model.
Recently, two separate studies demonstrated anti-inflammatory properties of PGD2 in an air-pouch model of inflammation induced by monosodium urate monohydrate crystals [ 13, 51].
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