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Lysozymes and other lytic proteins can be active against both Gram-positive and Gram-negative bacteria, potentially activating the Toll-related signaling pathway by releasing bacterial cell wall material [ 2, 16].
These patterns represent potentially activating features of the toxic compounds that may then be used to define new alerts.
B-SIFT presents the first generalized tool for systematic prediction of potentially activating missense mutations that are a result of increased protein fitness, thereby identifying potentially functional mutations that were previously ignored.
To further explore the possibility that changes in H3K4me2 marks may play a role in reactivation by potentially activating lytic genes for transcription via PTMs, we analyzed the H3K4me2 enrichment of the ICP0 promoter post-TCIE in both McKrae and KOS strains at 0.5, 1, 2 and 4 h post-TCIE.
SIRT1 levels increase with dietary restriction, potentially activating target genes leading to stress resistance and longevity.
IL-17 can induce fibroblasts to produce IL-6 potentially activating a positive feedback loop that strengthens Th17 inflammation [ 12].
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Akt activation, in turn, potentially activated MDM2, leading to enhanced p53 ubiquitination and potential blockage of GSK3β (Figure 2).
The potential downstream metabolic pathways potentially activated in OPC by AEF and the consequences of these activated pathways are discussed.
In HD, it appears that NMDA receptors of MSSNs are potentially activated at more hyperpolarized potentials, which could be deleterious for the cell.
Cbp binding potentially activates ligand localization for Csk kinase activity (Takeuchi et al., 2000; Wong et al., 2005).
Nucleotide sequence analysis revealed a single nucleotide mutation at codon 545 of PIK3CA in MKN1 and AGS cells (E545K and E545A, respectively, Additional file 11c), which suggested that AKT is potentially activated in these cells through mutational activation of PIK3CA.
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CEO of Professional Science Editing for Scientists @ prosciediting.com