Sentence examples for potentially a significant problem from inspiring English sources

In particular settings where delayed uptake of iron oxide-based agents are used, such as lymph node imaging, this is potentially a significant problem because the workflow does not allow for an MR-based attenuation correction map to be obtained prior to the agent's administration.

The difficulty of "confounding by indication" whereby the prognosis partly determines the choice of treatment, is potentially a significant problem for non randomised trials such as this [ 29].

Although regional failure is potentially a significant problem in anal cancer, 30 Gy appeared to be adequate for even macroscopic disease in the series of 45 patients from Nigro's group, suggesting high intrinsic sensitivity of this disease to the CRT combination (Nigro et al, 1983).

This potentially presents a significant problem in patients who need heparin for regular haemodialysis therapy, although the incidence rate for this population is currently not well researched.

While the doses of ET receptor blockers used in these trials were likely substantially higher than necessary, it is evident that ETA blockade-induced fluid retention is a significant problem potentially limiting this class of drug's clinical utility.

With security and compliance a key issue in today's business environment, this points to a significant problem that potentially puts the organisation at risk.

However, for many women, the risk of potentially life-threatening invasive recurrence remains a significant problem.

But it does point up a significant problem with the potentially cost-saving (and life-saving) innovations: they require regular, functioning, regularly maintained highway infrastructure.

Since counterfeit medications are a significant problem in Azerbaijan, this potentially puts the patient at risk.

To date, CINV remains a significant problem contributing to patient withdrawal from potentially curative chemotherapy [ 5, 8- 10].

Violence remains a significant problem.