To assess this, the safety and efficacy of the long-term dietary use of a clinoptilolite-rich tuff (Cp) in sows were investigated in two experimental designs, in terms of potential undesirable effects on the animals' health and the blood concentration of certain nutrients, as well as of any beneficial effect on their performance.
While the clinical significance of such relatively small changes is unclear, these findings provide a caution of potential undesirable effects of CO within the lungs even at low doses, which may have previously been overlooked.
These are some of the potential undesirable effects that need to be considered in regards to the publication of quality data.
Thus, in the 2013 campaign on information for breast cancer screening, the leaflet produced by the INCa included a new section describing the potential undesirable effects [ 38].
These studies should include an adequate description of contextual factors impacting at all stages along the causal chain, and be inclusive of reporting potential undesirable effects.
Drug toxicology (also termed pharmaceutical toxicology or safety pharmacology) is the study of the potential undesirable effects of drug candidates and drugs in the therapeutic range and above.
However, in apparent stark contrast to the many efforts aimed at exploiting desirable properties of NPs for improving human health are the limited attempts to evaluate potential undesirable effects of NPs when administered intentionally for medicinal purposes, or after unintentional exposure during manufacture or processing for industrial applications.
However, potential undesirable side-effects of long-term restricted diets should be taken into account.
Identification of potential targets for drugs is important for discovering new therapeutic applications as well as identifying potential undesirable side-effects ("off-target interactions").
To evaluate potential undesirable toxic effects of the nanoparticles towards healthy cells, PEGylated nanoparticles were incubated with hTERT-RPE-1 (RPE-1) cells, an immortalized human telomerase reverse transcriptase-retinal epithelial cell line.
