Sentence examples for potential trail from inspiring English sources

Planners and managers can utilize these results to identify strategies for maximizing greenway-related benefits among diverse groups of potential trail users.

In addition, screening of the F.D.A.-approved oncology drugs may provide insights into the clinical use of known agents, such as Bortezomib, as potential TRAIL sensitizers.

Compounds were considered potential TRAIL sensitizers if viability in the NB7+Casp8 + TRAIL condition was less than 50% of the vehicle-only control and at least 20% less than the viability of the NB7 + TRAIL and/or NB7+Casp8C360A + TRAIL conditions.

Thus the testing of potential TRAIL sensitizers against cells of various tissue types or against cancer cell lines harboring genetic deletions, mutations or amplifications of clinical significance may aid clinicians in assessing if certain agents may prove more effective in certain cancer types.

Following identification of mitoxantrone and mithramycin as potential TRAIL sensitizers, we investigated the effect of different TRAIL concentrations in combination with a single dose of these sensitizer drugs.

A total of fourteen potential TRAIL sensitizer leads, including six whose TRAIL sensitization activities were previously unknown, were identified from the screen.

According to SEC filings, Stanford Group Co., the investment advisory company affiliated with Stanford International, would get 3% commission on the aggregate sales of CDs by its advisers while the financial advisers would earn 1% up front and a potential trailing commission of another 1%.

We describe here the development of a novel 384-well high-throughput screening (HTS) strategy for identifying potential TRAIL-sensitizing agents that act solely in a caspase-8 dependent manner.

Thus, the use of such mutants in combination with CD40 targeting principally allows further reduction of potential TRAIL-related side effects in cases where the latter and the apoptotic effect in the targeted tumor make differential use of TRAILR1 and TRAILR2.

The response of adenomas and carcinomas was compared by a two-way analysis of variance of TRAIL-induced apoptosis (malignant potential × TRAIL concentration).

We have recently demonstrated that resveratol enhances therapeutic potential of TRAIL by upregulating death receptors (TRAIL/DR4 and TRAIL-R2/DR5) and also engaging mitochondrial pathway of apoptosis [2], [3].