MAP90 is a surrogate measure of APD90, the time at which the action potential reaches 90% repolarization from plateau potential to resting potential, as shown in Fig. 1.
This entry produces depolarization, and explains the return of the membrane potential to resting levels, when this entry is blocked.
In paralyzed larvae, the fictive correlate of this behavior, termed "beat-glide" swimming, presents as alternating bouts of rhythmic synaptic drive separated by short silent periods where the membrane potential returns to rest [ 22].
In DMH neurons, membrane depolarization from negative holding potentials (< −65 mV) or depolarization at the offset of the membrane response to hyperpolarization from potentials close to resting potential (−45 to −50 mV) evoked a transient depolarizing potential consistent with activation of a low-threshold T-type calcium conductance.
Both Nav1.8 and Nav1.9 channels are known to be expressed in some small diameter IB4+ neurons (Fang et al., 2006; Strickland et al., 2008) and Nav1.9, in particular, may begin to activate at potentials close to resting potentials we have observed (Rugiero et al., 2003; Coste et al., 2004; Zhao et al., 2011b).
The current generated by NaV1.9 is 'persistent' and can be activated at potentials close to resting membrane potential (∼−60 mV).
The potential explanation appears to rest on the gender differences in lean tissue mass content.
(breve{a}_{i}) describes the rate with which each neuron will reset its potential to the resting state in isolation when disconnected from the networks and external inputs.
c i > 0 denotes the rate at which a cell i resets its potential to the resting state when isolated from other cells and inputs; τ j ( t ) corresponds to the transmission delay.
(D=operatorname{diag}(d_{1}, d_{2},ldots, d_{n})) describes the rate with which each neuron will reset its potential to the resting state in isolation when disconnected from the networks and external inputs.
b i and η j denote the rate with which the i th neurons and j th neurons will reset their potential to the resting state in isolation when disconnected from the network and external inputs, respectively.
