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Some have suggested people such as Sergei Ivanov are being moved to neutralise any potential spheres of opposition to Putin among his old friends.
To evaluate clonogenic potential, spheres from each of the WT and TLX-silenced cells were dissociated and reseeded at a density of 1000 cells per well and analyzed for secondary sphere formation as an indicator of self-renewal potential.
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Bronze (the matter) is a potential sphere, and the cloak is an actual sphere.
Therefore the similarity of the pattern of cerebellar activity with the pattern of activity found in AIP (and their possible connections) expands the potential sphere of influence of the cerebellum.
Numerous studies have documented the presence of ALDHbright cells in several adult tissues and demonstrated that these cells carry significant stem/progenitor characteristics including stem cell markers, proliferative potential, sphere formation, clonogenicity, and multilineage differentiation.
On the other hand, in our preliminary data, NS-GFP cells showed an increased potential for sphere formation.
Site 1 within the G13A14A15A16 tetraloop also utilizes three potential outer-sphere ligands identified as A15 O5′/5′- pro-Rp OP and A16 5′- pro-Rp OP (Table 4).
Site 3 also involves several potential outer-sphere ligands identified as C7 O3′/O5′/5′- pro-Rp OP, A8 O5′/5′- pro-Rp OP, and G9 O5′ (Table 4).
Site 2 is located in the hairpin stem near the C10 5′-Pof– of the S-turn, where G17 O6, U18 O4, and G19 O6 act as potential outer-sphere ligands and C10 5′-PO4– likely contributes to electrostatic stabilization.
This tight packing of repulsive electronegative charges is dependent on the multidentate chelation of a Mg2+ ion, which involves an inner-shell ligand [5′- pro-Rp OP of G9 (G757)] and several potential outer-sphere ligands.
Site 4 is associated with the U5 G22 wobble base within the 5′ 3′ stem, with U5 O4, G22 O6/N7/5′- pro-Rp OP, and G23 O6/N7 acting as potential outer-sphere ligands and G22 5′-PO4– ensuring electrostatic stabilization.
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