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We assessed cultured human cancer cells for potential responsiveness to Johrei treatment from a short distance.
The set of genes for predicting potential responsiveness to arsenic was obtained from the Comparative Toxicogenomics Database (CTD).
Many of these genes are not well characterized, and their potential responsiveness to LIF could help unravelling their function.
It bears molecular similarities to HER2-amplified breast cancer, and is yet to be adequately assessed for potential responsiveness to anti-HER2 therapy.
This potential responsiveness to multiple endocrine therapies means that patients may continue to derive clinical benefit while avoiding the marked, and often distressing, adverse side effects associated with chemotherapy.
Biomarkers are defined as any molecule derived from a biological sample that can indicate current disease status, evaluate progression of the disease, or assess potential responsiveness to a particular medication [ 3].
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In addition, differences in tumorigenic potential and responsiveness to these agents are shown to be related to differences in gene expression between NCI60 cell lines with high and low tumorigenic potentials, as well as to gene expression markers of tumorigenic cancer cells.
Therefore, the EREs, though good indicators, only partially reflect a gene's potential for responsiveness to estrogens.
Additionally, CXCR4, the receptor for CXCL12, is overexpressed on CLL cells compared to normal B cells, and thus has the potential for enhanced responsiveness to CXCL12 signaling [5].
To assess whether these changes may distinguish AtCRT3 functions from that of typical CRTs, we measured the ER Ca2+-holding potential and the responsiveness to BK of the AtCRT3 complemented crt−/− mouse fibroblasts.
Age, sex, APOE, and AChEI administration were evaluated as potential predictors of responsiveness to AChEI treatment at the 6-month follow-up.
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