Sentence examples for potential pathogenic effects from inspiring English sources

The great majority of studies exploring potential pathogenic effects of engineered nanomaterials have been conducted in study settings mimicking the effects in healthy individuals, but only part of the world's population belongs to this group.

To investigate the potential pathogenic effects of Emuc both in vitro and in vivo, we designed an experiment of adenovirus-mediated gene delivery to cultured cells and mice (Fig. 1A).

Based on the growing body of evidence showing potential pathogenic effects of HIV-induced activation of pDC, we recently proposed that chronic activation of innate immune responses, rather than direct T cell activation, may play a major role in HIV pathogenesis [27].

Subsequent experiments revealed potential pathogenic effects of anti-LAMP-2 antibodies.

However, relatively little is known about the potential pathogenic effects of the human ACPA response.

We anticipate that these antibodies will provide us with new opportunities to investigate the potential pathogenic effects of human ACPAs.

Using PolyPHEN (4) and SIFT (5) software for predicting the potential pathogenic effect, the variant was likely to be disease-causing mutations.

In several inflammatory disorders, the potential pathogenic effect of inflammatory cytokines will depend on the balance in the cytokine network, particularly on the levels of counteracting anti-inflammatory mediators.

These data suggest that most of the variants despite being located in different domains of LRRK2 appear to exert a potential pathogenic effect possibly through an increased kinase activity, supporting a gain of function mechanism.

The potential pathogenic effect of the missense mutations on protein function was predicted using two software programs: PolyPhen (Polymorphism Phenotyping) (http://genetics.bwh.harvard.edu/pph/) and PANTHER (Protein Analysis Through Evolutionary Relationships) (http://www.pantherdb.org/).

Given the likely pathogenic effects of high C26:0 levels, our findings highlight the potential of modulating ELOVL1 activity in the treatment of X-ALD.