All nodes are potential message originators of anonymous communications.
This paper aims to explore dynamically the price and use comparison of generic and originator drugs in China, and estimate the potential savings of patients from switching originator drugs to generics.
Upon recognizing the potential, to then contact the originator for further discussions in route to establishing a mutually profitable and rewarding business relationship.
Based on the use of identical INNs and the potential differences between biosimilars and their originators, the Medicines and Healthcare Products Regulatory Agency (MHRA) and the ABPI recommend that a product's brand name be used when prescribing a biologic or biosimilar and when reporting adverse drug reactions associated with a biologic or biosimilar [ 34,57,58].
These data suggested potential differences in therapeutic effects between originator and generic products, while the clinical outcome study of a generic product conducted by the manufacturer indicated a certain degree of effectiveness.
The potential savings of patients from switching originator drugs to generics is 65%.
In this paper, we consider the optimal selling strategy for an asset securitization originator (the issuer) when the potential buyers hold diverse beliefs.
BSc1, when interchangeability is not allowed at all, is the strictest possible option, while BSc2 is a potential extreme case, with 80%% replacement of originator by biosimilar (e.g., in an extreme situation where the payer would oblige providers to replace the originator treatment).
The objective of this paper is to elaborate epidemiological, clinical and economic data on ESAs consumption in Greece, in order to determine potential cost savings by using biosimilar over originator ESAs under different dosing schemes for the management of the newly diagnosed chemotherapy-induced anemic patients.
Using the experience of other countries for reference, generic substitution can decrease pharmaceutical expenditure, with a potential saving of 66% for patients by switching from originator to generic drugs.
