Although the test yields quantitative results, the magnitude of IgE response does not necessarily serve as a quantitative estimate of sensitizing potential (Boverhof et al., 2008; Briatico-Vangosa et al., 1994; Isola et al., 2008; Kimber et al., 2007; UN, 2007a).
DAC inhibitors possessing class I inhibitory activity have shown the potential to sensitize many types of tumor cells [33], [34], including CLL [35], to tumor necrosis factor-related apoptosis inducing ligand (TRAIL).
There is a need for an increased efficiency with the provision of anti-D immunoglobulin, particularly in situations of potential sensitizing events.
Thus, a source of metal ion exposure with the potential to sensitize patients is present.
Despite a number of preclinical studies indicating potential radiation sensitizing effects of candidate therapeutics, few have been tested in clinical studies.
Therefore, targeting signaling cross-talks may have the potential to sensitize cancer cells to particular inhibitors.
Both would increase the Nav1.7 currents at small deviations from the resting potential and the likelihood of action potential initiation, presumably sensitizing the neurons expressing these channels to small depolarising stimuli.
In this study, we investigated the potential of PARPi to sensitize liver cancer cells to ionizing radiation.
Their expression was clearly correlated to perivascular and diffuse infiltrates in the synovial membranes of sensitized knees, in agreement with their chemotactic potential [ 46].
Out of the 18 articles included in this review 8 articles examined the provision of anti-D immunoglobulin when potential sensitizing events occur [ 13, 23, 24, 26- 30].
