Sentence examples for potential mode of action from inspiring English sources

Determining systemic dose in toxicology studies will increase the understanding of potential mode of action (MOA) reducing the use of animals by avoiding unnecessary additional MOA studies.

In addition, it has been shown that both compounds promote Ethidium Bromide (EtBr) accumulation in SA1199B, thus corroborating their potential mode of action as NorA inhibitors.

In addition, BRO therapy attenuated the increase in the pro-inflammatory eicosanoids PGE2, LTB4 and cysLT (Fig. 1b-d), suggesting that direct or indirect interference with the AA metabolic pathway could be a potential mode of action of BRO.

Inhibition of the key hydrolytic enzymes of the endocannabinoid system, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL), has been proposed as potential mode of action for various therapeutic applications.

Direct hydrolysis of feed in the rumen is a potential mode of action, but the importance of this mode needs to be quantified because of the relatively low exogenous hydrolase activity added compared with the total activity present in the rumen.

This was an interesting result because its potential mode of action differs considerably from traditional antibiotic agents.

Uncertainties in understanding all potential modes-of-action for asthma induction and elicitation hinders design of hazard characterization and risk assessment methods that adequately screen and protect against hazardous chemical exposures.

Thus, DNA microarray experiments would be extremely helpful to study effects on the transcription of genes involved in these processes, to provide more insight in potential mode of actions of rhodomyrtone.

The third paper of this special issue presents a brief overview of the helminth-associated immune response, the currently available helminth secretome data, some major secretome-derived immunomodulatory molecules, their potential mode of actions and the applicability of helminth-derived therapeutic proteins in the treatment of allergic and autoimmune inflammatory disease.

Overall, PARP inhibitors represent a potentially important new class of anti-cancer agents with two potential modes of action, as single agents causing synthetic lethality and as chemo-potentiating agents.

A regulatory model, miRNA targeting of intron-containing pre-mRNAs phased sRNAs—targeting of mature mRNAs is pre-mRNAs phasedfurther expandsRNAs targeting mofes of action of plant mature.