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Models assessing potential intermediaries were limited to participants with baseline data on all of these variables (N = 2,949).
For analyses of potential intermediaries, models were restricted to the 2,949 participants with complete data on the covariates considered.
Our study allows the investigation of specific miRNA:mRNA interactions based on anti-correlated expression, and allows us to focus on known oxidative stress and cytoskeletal pathway mRNAs as attractive potential intermediaries between miRNAs and phenotypes.
Additional adjustment for potential intermediaries, such as fainting in the past year, standing balance score, cystatin C level, and number of prescription medications, accounted for some of the increased risk associated with diabetes (1.41 [1.05–1.88]) and insulin-treated diabetes (2.24 [1.2.24.03]).
Given the complex interplay between components of the immune system, metabolic factors, CMV and ageing, as well as the contribution of potential intermediaries such as oxidative stress and inflammation to these processes, bidirectional or cyclical relationships between these factors cannot be ruled out.
Relative to participants without diabetes, those with any diabetes had an elevated risk of hospitalization for an injurious fall (hazard ratio [HR] 1.48 [95% CI 1.12 1.95]) (Table 2), even after adjustment for potential intermediaries (history of fainting, standing balance score, cystatin C level for renal function, and number of prescription medications) (1.41 [1.41–1.41]).
Similar(53)
"Four days ago, an individual approached the British embassy in Baghdad, presenting himself as a potential intermediary with the captors," Mr Straw said.
That is why today French government agencies are still prevented by law from collecting data about ethnicity, considered a potential intermediary community between state and citizen.
Mr. Rahmani, who lived under government protection in Kabul, was viewed as a potential intermediary in any future negotiations between the government and the Taliban.
By the time he has been encouraged by his admirers to lead a peace march across Northern Ireland and to claim that he has been mooted as a potential intermediary between Begin and Sadat to reconcile warring parties in the Middle East, then what Davies calls Savile's messiah complex has taken up every inch of space in his head.
Actinobacillus succinogenes naturally produces high concentrations of succinate, a potential intermediary feedstock for bulk chemical productions.
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