As AhR may serve as a potential biomarker for sensitivity to AF, we examined the cellular localization as well as the requirement of endogenous levels of AhR for AF sensitivity in MDA-MB-468 and Cal51 cells.
Fifty-one percent (41/81) of the BRCA-likeCGH tumors were ER-positive, making this the first study reporting on a potential marker for sensitivity to intensified DSB-inducing agents within the sporadic ER-positive breast cancer population.
To be useful as an indicator of individual MT expression, and thus as a potential biomarker for sensitivity to metal intoxication, MT expression measured in a readily accessible sample (i.e., blood) would have to correlate with individual tissue protein levels.
Complex, protein truncating TP53 mutations in BRCA1-mutated tumors may be a direct consequence of genomic instability caused by BRCA1 loss, therefore, the presence of these types of TP53 mutations in sporadic BLBCs might be a hallmark of BRCAness and a potential biomarker for sensitivity to PARP inhibition.
The associated potential for increased sensitivity towards analytes is of significance to the analytical and biophysical sector.
It has been shown to exhibit several advantages over other resonant methods, in particular a potential for higher sensitivity and rejection of common mode noise.
Not only does it provide a potential for high sensitivity and flexible sensor design, but also opens up a new way to design micro sensors and integrated optical circuits.
Thus, these nanocomposites containing semiconductors like SnO2 and ZnO are likely to overcome several problems that currently exist with devices fabricated using either just with SnO2 or ZnO, and the resulting system has the potential for tunable sensitivity and selectivity for many applications [10, 27, 28].
These demonstrated the potential for increased sensitivity in statistical analysis using geometrical models of the white matter tracts and tract-based analysis.
Apart from inoculation of susceptible hosts (bioassay), only in vitro amplification by serial protein misfolding amplification (sPMCA) [17], [26], [27], [28] offers the potential for comparable sensitivity.
