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To compare the potential for elaboration across external (dietary) compounds from purely structural considerations, we used a metric called "biochemical scope" [ 33] that reflects the number of simplest consecutive chemical reactions (called "biochemical generations") needed to reach any compound in the network from a dietary starting point (Fig. 10).
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All these dimers possess a promising potential for the elaboration of semiconducting materials with a charge transport of higher dimensionality compared to quaterthiophene.
It follows, that when enzymatic connectivity in the vicinity of different dietary entry points vary, ecologically-distinct taxa should have different potential for color elaboration and diversification.
To investigate in silico the potential for such elaboration, we used the docking program ligtor to screen for beneficial substitutions/modifications of either the acetamido or the sulfonamide group, while keeping the rest of the molecule constant.
They also have the potential for further synthetic elaboration, to provide new probes for the study of InsP and PP-InsP signalling.
Second, the evolutionary potential for carotenoid color elaboration and diversification should differ predictably among clades depending on the density of enzymatic reactions, overlap in biochemical domains of distinct dietary carotenoids, and diversity of dietary carotenoids in species' metabolic networks (e.g., [ 53]).
Each of these macrocycles was based around a distinct molecular scaffold and contained natural product-like structural features (e.g., three-dimensionality and multiple hydrogen bond donors and acceptors) as well as synthetic handles for potential further elaboration.
Potential for narrative and symbolic elaboration may be greatest for Penba Wangdu, also of Tibet, and Tenzin Norbu, of Nepal, though their paintings on view here are disappointingly decorous.
One likely explanation for this apparent paradox is that in high-predation, where natural selection is stronger on colour [19] (but see [46]), the potential for sexual selection to affect elaboration of male colour is limited.
It also cries out for elaboration.
"There's really no need for elaboration," Vanzetti adds.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com