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Although our standardized protocol calls for prophylactic treatment 1 day before virus inoculation to maximize the potential for discerning antiviral efficacy of new drugs in initial in vivo tests, we show here that postexposure drug initiation (beginning 1, 3, or 7 days after HIV-1 inoculation) also renders potent antiviral efficacy.
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This article considers these methodological issues and offers an additional methodology focused on fetal neurobehavior for discerning potential mechanisms that may mediate associations between maternal psychological functioning and the developing fetal nervous system.
Two other large occupational cohort studies (i.e., Pinkerton et al., 2004, and Coggin et al., 2003) are generally highlighted as additional important data for discerning potential effects between formaldehyde and the different cancers.
However, a standard evaluation method for discerning the functional potentials harbored within the genome or metagenome has not yet been established.
Annex 2 was deemed useful for assessing communicable diseases, and less helpful for discerning other types of potential PHEICs.
Targeting ALDH as a potential approach for cancer cell labeling might be an appropriate "tracer" for discerning drug-sensitive and drug-resistant phenotypes of cancers to evaluate the effectiveness of novel therapies (27).
The identification of potential endogenous or synthetic ligands for orphan receptors in the steroid receptor superfamily is important both for discerning endogenous regulatory pathways and for designing receptor inhibitors.
Future screens of synthetic libraries of short peptides with anti-cancer potential in zebrafish embryos hold great promise for finding the highly selective and active variants, and for discerning their mode-of-action.
FOR discerning drug users, these are high times.
All in all, a remarkable year for discerning diners.
Now there are single-origin varieties for discerning chocoholics.
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CEO of Professional Science Editing for Scientists @ prosciediting.com