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However, the reduced vitality of plants that have naturally developed resistance and the undesired effects on plant-hormone homeostasis observed here with overexpression of P450 SU1 highlight some of the potential deleterious outcomes that will need to be addressed for successful exploitation of this promising area.
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Moreover, toxicity is significant with potentially deleterious outcome.
However, in this study, hypothermia lasted only 2 hours, and potential deleterious effect could be observed.
The potential deleterious effect of hypoxia during the resuscitative efforts has been also found in another recent retrospective study [100].
A score threshold of ≤−2.0 was used to classify a variant as having potential deleterious effect.
This observation is at odds with the potential deleterious effect of angiotensin II.
Without a sufficiently strong inverse-correlation between flexibility and deleterious potential, the probability of deleterious outcomes would have been too high because most of the random variation is not beneficial.
St John's wort reduces plasma levels of the active metabolites of three chemotherapy agents: irinotecan, imatinib mesylate, and docetaxel, with potential deleterious consequences on treatment outcome [ 15].
Based on the lack of evidence documenting improved outcome, potential deleterious effects, and substantial economic strain on the health care system, we agree with the recent review by Alderson and colleagues [ 19].
Physicians are more frequently encouraging patients to try yoga as an alternative to more invasive treatments that have inconsistent outcomes and potential deleterious side effects.
On the other hand, potential deleterious effects of severe hypoglycemia on CV outcomes may be overestimated because patients experiencing severe hypoglycemia had a longer duration of diabetes and greater burden of microvascular complications.
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