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Given the observation of dopamine transmission deficits in several LRRK2 mutant rodent models [21], [39], [40], [41], the potential connection of PKA-LRRK2 signaling indicates an attractive cellular pathway for the future dissection of the molecular mechanism underlying LRRK2 mutations in the pathogenesis of PD.
The mechanisms and potential connection of the lipid-lowering properties of PPARα agonists to tumor suppression are still poorly understood.
We thus think that the potential connection of these genes to MS is a natural target for a further study.
Interestingly, total egg numbers laid were significant higher in Or7a mutant and Or7a neuron ablated flies, implying a potential connection of oviposition site selection and egg deposition number.
Although we were unable to obtain additional evidence of the potential connection of this family with polymerases, it is tempting to speculate that these proteins might contain an extremely diverged version of the PALM domain.
To further investigate a potential connection of SGOL1 and Ska complex, we depleted Ska1 and SGOL1 in the C13orf3 BAC-tagged HeLa cell line and monitored possible changes in C13orf3 protein levels by western blot analysis.
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However, to fully understand the reality and the potentials embedded in the present, one has to broaden the scope to see actual and potential connections of an issue.
These data provide a comprehensive map describing the potential connections of neurons in the MB lobes.
"I still think the shooter was who everyone thinks it was: Orlando Anderson," says Randall Sullivan, author of the meticulously reported LAbyrinth, which traces the connections between the disgraced Rampart officers of the LAPD and their potential connection to the death of The Notorious BIG.
Financial incentives are often disfavored because of potential connection to commercial trade.
Most importantly, the KSR1-regulated phosphoproteomic analysis has identified phospho-DBC1 as a potential connection to its modulation of p53 transcriptional activity here.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com