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On the backend, you could imagine that developers build the systems and deploy them without being totally sure how they will behave, and unable to anticipate the potential adverse outcomes they might generate.
An assessment of toxicology tests currently used in safety evaluation revealed that these tests are expected to identify any potential adverse outcomes resulting from epigenetic changes.
With rapid development of novel nanotechnologies that incorporate engineered nanomaterials (ENMs) into manufactured products, long-term, low dose ENM exposures in occupational settings is forecasted to occur with potential adverse outcomes to human health.
Presently available mouse models can achieve a high degree of predictive validity for positive outcomes of experimental therapies, but they have been less successful in identifying potential adverse outcomes that can occur in human trials.
This is a space where participants can experience the effects of the substance they've consumed, and they can also be monitored for potential adverse outcomes like overdose.
The questionnaire monitors nine potential adverse outcomes using automated calls and telephone consultations by occupational therapists.
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The tolerable upper intake level (UL) (1000 μg/day)of folic acid was established as one-fifth of the lowest observed adverse effect level (5000 μg/day) associated with a potential adverse outcome [32].
Because basic toxicological data is unavailable for the majority of industrial compounds, High Throughput Screening (HTS) assays using the embryonic and larval zebrafish provide promising approaches to define bioactivity profiles and identify potential adverse outcome pathways for previously understudied chemicals.
8 Our data raise concern about the potential adverse outcome events of non-depolarizing neuromuscular blocking agents, and further targeted research is warranted to resolve remaining questions.
14 There has been considerable concern that suicidal behavior is a potential adverse outcome of prescription drug use, including antidepressant and anticonvulsant agents.
As long-term thiopurine therapy remains central to the management of inflammatory bowel diseases it is essential that both patients and clinicians are aware of this potential adverse outcome.
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